Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

Hepatitis C virus (HCV) is hepatotropic and only infects humans and chimpanzees.Consequently, an immunocompetent small animal model is lacking.The restricted tropism of HCV likely reflects specific host factor requirements.We investigated if dominant restriction factors expressed in non-liver or non-human cell lines inhibit Battery HCV propagation

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Mitigation of mutual coupling in microstrip antenna arrays

This article demonstrates the alleviation of mutual coupling of a simple and low-cost four-element microstrip array antenna by loading MINI-OMEGAS I-shaped slot-type electromagnetic band gap structure in the ground plane.FR-4 glass epoxy is used as dielectric substrate.Moreover, the proposed array antenna shows a better performance in terms of mult

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Significant Effects of Maternal Diet During Pregnancy on the Murine Fetal Brain Transcriptome and Offspring Behavior

BackgroundMaternal over- and undernutrition in pregnancy plays a critical role in fetal brain development and function.The effects of different maternal diet compositions on intrauterine programing of the fetal brain is a lesser-explored area.The goal of this study was to investigate the impact of two chowmaternal diets on fetal brain gene expressi

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Challenges faced by older adults caring for their parents and their relationship with depressive status: Examining internet use as a moderator

Amid accelerating population ageing, China has witnessed a growing number of caregivers aged 60 and over.Older adults caring for their parents may represent a notable family caregiving paradigm in the longevity era, yet their unique challenges and associated health impacts deserve more attention.Using two waves of data from the China Longitudinal A

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